CAS NO: | 5467-84-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 5467-84-5 |
Canonical SMILES | O=C(NCCC1=CC=CC=C1)NCCC2=CC=CC=C2 |
分子式 | C17H20N2O |
分子量 | 268.4 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml,Ethanol: 1 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | N,N’-Diphenethylurea is a bacterial metabolite that has been found inStreptomycesand has diverse biological activities.1It inhibitsStreptomyceschitin synthase 1 (IC50= 14 µg/ml) but notC. albicanschitin synthase 2 when used at concentrations up to 280 µg/ml. N,N’-Diphenethylurea is active against the fungusC. neoformansand the plant pathogenic fungusR. solani(MIC = 50 µg/ml for both).2It enhances insulin-induced adipocyte differentiation in 3T3-L1 and C3H/10T1/2 cells when used at concentrations of 30 and 100 µM.3 1.Iwai, Y., Hirano, A., Awaya, J., et al.1,3-Diphenethylurea from Streptomyces sp. No. AM-2498J. Antibiot. (Tokyo)31(4)375-376(1978) 2.Kim, N.R., Hwang, E.I., Bong, S.K., et al.Isolation of Candida albicans chitin synthase 1 inhibitor from Steptomyces sp. A6705 and its characterizationJ. Microbiol. Biotechnol.15(4)895-898(2005) 3.Choi, S.-S., Cha, B.-Y., Kagami, I., et al.N,N’-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cellsJ. Antibiot. (Tokyo)64(3)277-280(2011) |