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Etodolac Acyl Glucuronide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Etodolac Acyl Glucuronide图片
CAS NO:79541-43-8
包装:1mg
市场价:2404元

产品介绍
A phase II metabolite of etodolac
Cas No.79541-43-8
别名依托度酸酰基-Β-D葡糖苷酸
Canonical SMILESO=C(O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]([C@H]1O)C(O)=O)CC(C2=C3C4=CC=CC(CC)=C4N2)(OCC3)CC
分子式C23H29NO9
分子量463.5
溶解度Methanol: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A10, and UGT2B7.

1.Kutsuno, Y., Itoh, T., Tukey, R.H., et al.Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 miceDrug Metab. Dispos.42(7)1146-1152(2014)