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N-desethyl Brinzolamide(oxalate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-desethyl Brinzolamide(oxalate)图片
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
An active metabolite of brinzolamide
Canonical SMILESCOCCCN(S1(=O)=O)C[C@H](N)C2=C1SC(S(=O)(N)=O)=C2.OC(C(O)=O)=O
分子式C10H17N3O5S3·C2H2O4
分子量445.5
溶解度DMSO: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively).

1.Kim, C.-Y., Whittington, D.A., Chang, J.S., et al.Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IVJ. Med. Chem.45(4)888-893(2002)