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LSD1-IN-6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LSD1-IN-6图片
CAS NO:2035912-43-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
LSD1-in-2 (Compound 4m) 是一种有效、可逆的赖氨酸特异性去甲基化酶 (LSD1) 抑制剂,IC50 值为 123 nM。LSD1-in-2 (4m) 能增加组蛋白 H3 Lys4 的二甲基化,但对 LSD1 的表达无作用。
Cas No.2035912-43-5
Canonical SMILESOC1=C(O)C=C(Br)C(/C=C/C2=CC=C(/C(N)=N/O)C=C2)=C1
分子式C15H13BrN2O3
分子量349.18
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 123 nM (LSD1)[1]

[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.