| CAS NO: | 808750-39-2 |
| 包装: | 1mg |
| 市场价: | 1890元 |
| Cas No. | 808750-39-2 |
| Canonical SMILES | CO[C@@H]1[C@@]23[C@](C(C4=CC=CC(OC)=C41)=O)([C@@H]([C@@H]([C@](O)([C@@H]3O)C([C@H]5[C@@H](O5)C)=O)C)O)O2 |
| 分子式 | C21H24O9 |
| 分子量 | 420.4 |
| 溶解度 | DMSO: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mensacarcin is a bacterial metabolite that has been found inS. bottropensisand has anticancer activity.1,2It is cytostatic in the NCI-60 panel of cancer cell lines (mean IC50= 1.3 µM) and cytotoxic to HepG2, HM02, KATO III, and MCF-7 cells (IC50s = 0.4-50 µM).1Mensacarcin induces apoptosis in SK-MEL-28 and SK-MEL-5 melanoma cells.2 1.Maier, S., PflÜger, T., Loesgen, S., et al.Insights into the bioactivity of mensacarcin and epoxide formation by MsnO8Chembiochem15(5)749-756(2014) 2.Plitzko, B., Kaweesa, E.N., and Loesgen, S.The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cellsJ. Biol. Chem.292(51)21102-21116(2017) |
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