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Amycolatopsin C
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Amycolatopsin C图片
包装与价格：
包装价格(元)
100µg电议
500µg电议

产品介绍
A polyketide macrolide with antimycobacterial and anticancer activities
Canonical SMILESCC(/C=C(CO)/C=C(OC)/C=C1\C)C(O[C@@H]2[C@H](O)[C@@H](O)[C@H](OC)[C@@H](C)O2)/C(C)=C/C(C)=C/C(C)=C\C(O)C(OC)CC([C@H](C)[C@@]3(O)[C@H](OC)[C@@H](O)[C@@](O)(C)[C@@H](CCCOC)O3)OC1=O
分子式C47H76O17
分子量913.1
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Amycolatopsin C is a polyketide macrolide originally isolated fromAmycolatopsisthat has antimycobacterial and anticancer activities.1It is active againstM. bovisandM. tuberculosis(IC50s = 2.7 and 5.7 µM, respectively) but notB. subtilis,S. aureus,E. coli, orP. aeruginosa(IC50s = >30 µM for all). Amycolatopsin C is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 10 and 5.9 µM, respectively).

1.Khalil, Z.G., Salim, A.A., Vuong, D., et al.Amycolatopsins A-C: Antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494J. Antibiot. (Tokyo)70(12)1097-1103(2017)