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Tryptoquivaline D
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tryptoquivaline D图片
CAS NO:60676-56-4
包装与价格:
包装价格(元)
250µg电议
1mg电议

产品介绍
Tryptoquivaline D 是烟曲霉的一种真菌代谢物。
Cas No.60676-56-4
Canonical SMILESON1[C@@]2([H])[C@]3(C[C@](N4C(C5=CC=CC=C5N=C4[C@H](C(C)C)OC(C)=O)=O)([H])C(O3)=O)C6=CC=CC=C6N2C([C@@H]1C)=O
分子式C28H28N4O7
分子量532.5
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 µM.1Tryptoquivaline D (1-100 µM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.2

1.Prata-Sena, M., Ramos, A.A., Buttachon, S., et al.Cytotoxic activity of secondary metabolites from marine-derived fungus Neosartorya siamensis in human cancer cellsPhytother. Res.30(11)1862-1871(2016) 2.Ramos, A.A., Castro-Carvalho , B., Prata-Sena, M., et al.Can marine-derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin• An in vitro survey unveils interactions against lung cancer cellsEnviron. Toxicol.35(4)507-517(2020)