| CAS NO: | 86933-99-5 |
| 包装: | 1mg |
| 市场价: | 7938元 |
| Cas No. | 86933-99-5 |
| Canonical SMILES | CC(N(O)CCC[C@@H](C(O)=O)NC([C@H]([C@H](O)C)NC(C1=C(C(O)=CC=C1)O)=O)=O)=O |
| 分子式 | C18H25N3O9 |
| 分子量 | 427.4 |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Vanoxonin is a bacterial metabolite that has been found inS. hirsuta.1It forms a complex with vanadium, and the complex inhibits thymidylate synthetase with an IC50value of 0.7 µg/ml. The vanoxonin-vanadium complex is cytotoxic to L1210 leukemia cells (MIC = 25 µg/ml) and increases survival in Ehrlich murine spontaneous adenocarcinoma and L1210 mouse tumor models. 1.Kanai, F., Sawa, T., Hamada, M., et al.Vanoxonin, a new inhibitor of thymidylate synthetaseJ. Antibiot. (Tokyo)36(6)656-660(1983) |
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