| CAS NO: | 1623153-14-9 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 1623153-14-9 |
| Canonical SMILES | CC1(C)CC[C@@H](O)[C@@]2(C)[C@@]1([H])[C@H](OC(CCCCC)=O)C=C3[C@]2(O)COC3=O |
| 分子式 | C21H32O6 |
| 分子量 | 380.5 |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Isonanangenine B is a drimane sesquiterpene lactone that has been found inAspergillus.1,2It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 µM. Isonanagenine B (18.42 µM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells. 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) 2.Felix, S., Sandjo, L.P., Opatz, T., et al.SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expressionBeilstein J. Org. Chem.92866-2876(2013) |
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