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Dasatinib metabolite M6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dasatinib metabolite M6图片
CAS NO:910297-53-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Dasatinib metabolite M6 (Dasatinib carboxylic acid) 是 Dasatinib 的氧化代谢物。Dasatinib 是一种具有口服活性的,ATP 竞争性的,双重 Src/Bcr-Abl 抑制剂,具有有效的抗肿瘤活性。
Cas No.910297-53-9
别名达沙替尼羧酸; Dasatinib carboxylic acid
分子式C22H24ClN7O3S
分子量501.99
溶解度DMSO : 100 mg/mL (199.21 mM; Need ultrasonic)
储存条件Store at -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib . Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor[1].

[1]. Lisa J Christopher, et al. Biotransformation of [14C]dasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab Dispos. 2008 Jul;36(7):1341-56.