您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > CCT245232
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CCT245232
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CCT245232图片
CAS NO:1693731-14-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
CCT245232 是热激因子 1 (HSF1) 的有效抑制剂。HSF1 是热激反应的主要调节因子,其中多个基因被诱导以响应温度升高和其他压力。CCT245232 具有研究增殖性疾病的潜力,例如癌症 (信息提取自专利 WO2015049535A1)。
Cas No.1693731-14-4
分子式C27H23N3O4
分子量453.49
溶解度DMSO : 41.67 mg/mL (91.89 mM; ultrasonic and warming and heat to 60℃)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CCT245232 is a potent inhibitor of heat shock factor 1 (HSF1). HSF1 is the master regulator of the heat shock response, in which multiple genes are induced in response to temperature increase and other stresses. CCT245232 has the potential for the research of proliferative diseases, such as cancer (extracted from patent WO2015049535A1)[1].

[1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. Patent WO2015049535A1.