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5(6)-Carboxyfluorescein(5(6)-FAM)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5(6)-Carboxyfluorescein(5(6)-FAM)图片
CAS NO:72088-94-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1g电议

产品介绍
5(6)-Carboxyfluorescein (5(6)-FAM) (5(6)-FAM) 是一种胺反应性 pH 敏感的绿色荧光探针。 5(6)-Carboxyfluorescein (5(6)-FAM) (5(6)-FAM) 可用于标记蛋白质、肽和核苷酸。 5(6)-Carboxyfluorescein (5(6)-FAM) 可用于检测体内肿瘤区域。
Cas No.72088-94-9
别名5(6)-羧基荧光素; 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
Canonical SMILESOC1=CC=C(C2(O3)C(C=C(C(O)=O)C=C4)=C4C3=O)C(OC5=C2C=CC(O)=C5)=C1.OC6=CC=C(C7(O8)C(C=CC(C(O)=O)=C9)=C9C8=O)C(OC%10=C7C=CC(O)=C%10)=C6
分子式C21H12O7
分子量376.32
溶解度DMSO : ≥ 41 mg/mL (108.95 mM)
储存条件-20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume.

[1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66.