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3-Hydroxy-4-methoxycinnamic acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3-Hydroxy-4-methoxycinnamic acid图片
CAS NO:537-73-5
包装:20mg
市场价:767元

产品介绍
3-Hydroxy-4-methoxycinnamic acid (3-Hydroxy-4-methoxycinnamic acid) 是一种具有抗糖尿病活性的肉桂酸衍生物。
Cas No.537-73-5
别名3-羟基-4-甲氧基肉桂酸,3-Hydroxy-4-methoxycinnamic acid
化学名(E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid
Canonical SMILESCOC1=C(C=C(C=C1)C=CC(=O)O)O
分子式C10H10O4
分子量194.18
溶解度DMF: 20 mg/mL,DMF:PBS(pH 7.2)(1:6): 0.14 mg/mL,DMSO: 15 mg/mL,Ethanol: 10 mg/mL
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 μM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use.

References:
[1]. Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204.