CAS NO: | 1870899-46-9 |
包装: | 250mg |
市场价: | 14095元 |
Cas No. | 1870899-46-9 |
分子式 | C32H40N2O9 |
分子量 | 596.67 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | DBCO-Amide-PEG5-acid is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs)[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Vukic Soskic, et al. Method for binding biologically active molecules to surfaces. DE102014215208A1. |