| CAS NO: | 372-66-7 |
| 包装: | 500mg |
| 市场价: | 1210元 |
| Cas No. | 372-66-7 |
| 别名 | 6-氨基-2-甲基-2-庚醇 |
| Canonical SMILES | CC(N)CCCC(C)(O)C |
| 分子式 | C8H19NO |
| 分子量 | 145.2 |
| 溶解度 | DMF: 15mg/mL,DMSO: 10mg/mL,Ethanol: 15mg/mL,PBS (pH 7.2): 10mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Heptaminol is an aliphatic amine with cardiotonic and sympathomimetic activities.1,2,3It decreases the amplitude of peak calcium currents by 30% in isolated guinea pig ventricular myocytes when used at a concentration of 100 µM.1Heptaminol inhibits norepinephrine uptake and induces catecholamine release in primary bovine chromaffin cells.3,2It increases blood pressure in cats when administered intravenously at a dose of 15 mg, an effect that can be blocked by reserpine .4 1.Peineau, N., Mongo, K.G., Le Guennec, J.-Y., et al.Alteration of the L-type calcium current in guinea-pig single ventricular myocytes by heptaminol hydrochlorideBr. J. Pharmacol.107(1)104-108(1992) 2.Grobecker, H.On the mode of action of heptaminolNaunyn Schmiedebergs Arch Pharmakol.266(4)339-340(1970) 3.Delicado, E.G., Fideu, M.D., Miras-Portugal, M.T., et al.Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cellsBiochem. Pharmacol.40(4)821-825(1990) 4.Garrett, J., Osswald, W., and Goncalves Moriera, M.Mechanism of cardiovascular actions of heptanolaminesBr. J. Pharmacol. Chemother.18(1)49-60(1962) |
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