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L-Palmitoylcarnitine TFA
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
L-Palmitoylcarnitine TFA图片
包装与价格：
包装价格(元)
10mg电议
50mg电议

产品介绍
L-PalmitoylcarnitineTFA是一种长链酰基肉碱和脂肪酸代谢产物，在缺血期间积聚于肌膜并扰乱膜脂环境。L-PalmitoylcarnitineTFA通过与Kir6.2的相互作用抑制KATP通道活性，而不影响单通道电导。
Canonical SMILESCCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O.OC(C(F)(F)F)=O
分子式C25H46F3NO6
分子量513.63
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].

L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 µM)[1].

[1]. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441(2-3):200-207.