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Kynuramine dihydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Kynuramine dihydrochloride图片
CAS NO:36681-58-0
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Kynuramine 是一种内源性胺,是血浆胺氧化酶 (amine oxidase) 的荧光底物和探针。
Cas No.36681-58-0
分子式C9H14Cl2N2O
分子量237.13
溶解度DMSO : 125 mg/mL (527.14 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase[1][2].

Kynuramine inhibits both presynaptic and postsynaptic α-adrenoceptors in vitro[2].Kynuramine has been shown to act as a partial agonist on serotonin receptors in dog cerebral arteries[2].Kynuramine (20 μg/mL) frequently causes a small contraction of the ileum but failed to alter the twitch response to cholinergic stimulation[2].

Kynuramine may serve a physiological role in the modulation of female sexual behavior[3]. Kynuramine increases heart rate and blood pressure in pithed rats[4].

[1]. J B Massey, et al. Kynuramine, a fluorescent substrate and probe of plasma amine oxidase. J Biol Chem. 1977 Nov 25;252(22):8081-4.
[2]. T D Johnson, An alpha-adrenoceptor inhibitory action of kynuramine. Eur J Pharmacol. 1981 Jul 10;72(4):351-6.
[3]. S D Mendelson, et al. Intraventricular administration of l-kynurenine and kynuramine facilitates lordosis in the female rat. Eur J Pharmacol. 1987 Oct 27;142(3):447-51.
[4]. T D Johnson, et al. Blood pressure and heart rate effects of kynuramine in pithed rats. Eur J Pharmacol. 1983 Feb 18;87(2-3):323-6.