卡托普利二硫化物是卡托普利的代谢物,具有抗高血压活性。
Cas No. | 64806-05-9 |
别名 | 卡托普利二硫化物,SQ 14551 |
Canonical SMILES | O=C(O)[C@H]1N(C([C@H](C)CSSC[C@@H](C)C(N2CCC[C@H]2C(O)=O)=O)=O)CCC1 |
分子式 | C18H28N2O6S2 |
分子量 | 432.6 |
溶解度 | DMSO: slightly soluble,Ethanol: slightly, sonicated |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril . Captopril disulfide is the main degradation product of captopril and is formed by oxidation. It is a potential impurity in commercial preparations of captopril. Captopril disulfide inhibits angiotensin I-induced increases in mean arterial pressure in anesthetized dogs (ID50 = 0.231 mg/kg, i.v.). |