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S-23
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S-23图片
CAS NO:1010396-29-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
S-23 是一种具有口服活性的选择性雄激素受体调节剂 (SARM),Ki 为 1.7 nM。
Cas No.1010396-29-8
别名(S)-2-(芴甲氧羰基)-3-联苯基氨基丙酸
Canonical SMILESO=C([C@](O)(C)COC1=CC(F)=C(Cl)C=C1)NC2=CC=C(C#N)C(C(F)(F)F)=C2
分子式C18H13ClF4N2O3
分子量416.8
溶解度DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 14 mg/ml,Ethanol: 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

S-23 is a selective androgen receptor modulator (SARM). It binds to the AR (Ki = 1.7 nM) and induces AR-mediated transcriptional activation in CV-1 cells expressing the human receptor when used at a concentration of 10 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. It decreases testicular sperm concentration without reducing mounting behavior or the number of intromissions in intact rats when administered in combination with estradiol benzoate . S-23 (3 mg/kg) also increases preference for sexually active intact males when administered to ovariectomized female rats.