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Bacopaside X
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bacopaside X图片
CAS NO:94443-88-6
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Bacopaside X 存在于 Bacopa monnieri 中，显示出对 D1 受体的结合亲和力。
Cas No.94443-88-6
别名假马齿苋皂苷VII,Bacopaside VII
Canonical SMILESC[C@]([C@]1([H])CC2)(CC[C@]3([H])[C@@]1(CC[C@H](O[C@@](OC[C@H](O)[C@@H]4O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)([H])[C@@H]4O[C@]6([H])O[C@@H](CO)[C@H](O)[C@H]6O)C3(C)C)C)[C@@]7(CO8)[C@@]2([H])[C@]([C@@](C)(O)C[C@H](/C=C(C)/C)O9)([H])[C@@]89
分子式C46H74O17
分子量899.1
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bacopaside X is a triterpenoid saponin that has been found in B. monniera and has antifungal and anticancer activities.1,2,3 It inhibits the growth of the fungi C. albicans, C. neoformans, and A. fumigatus (MIC = 50 μg/ml for all).2 Bacopaside X decreases the proliferation of MDA-MB-231, SHG44, HCT8, A549, and PC3M cancer cell lines with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 μM, respectively.3 It reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 μmol/kg.

|1. Zhou, Y., Shen, Y.-H., Zhang, C., et al. Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models. J. Nat. Prod. 70(4), 652-655 (2007).|2. Li, X.-C., ElSohly, H.N., Nimrod, A.C., et al. Antifungal jujubogenin saponins from Colubrina retusa. J. Nat. Prod. 62(5), 674-677 (1999).|3. Peng, L., Zhou, Y., Kong, D.Y., et al. Antitumor activities of dammarane triterpene saponins from Bacopa monniera. Phytother. Res. 24(6), 864-868 (2010).