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Nefopam HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nefopam HCl图片
CAS NO:23327-57-3
包装:50mg
市场价:504元

产品介绍
Nefopam HCl (Fenazoxine hydrochloride) 是一种中枢作用但非阿片类镇痛药,用于缓解中度至重度疼痛。
Cas No.23327-57-3
别名盐酸奈福泮; Fenazoxine hydrochloride
化学名5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride
Canonical SMILESCN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl
分子式C17H19NO.HCl
分子量289.8
溶解度Limited solubility
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo[1][2].

Nefopam hydrochloride (Fenazoxine hydrochloride) is a non-opioid, non-steroidal, centrally acting analgesic drug that is derivative of the non-sedative benzoxazocine[1].Constitutively elevated β-catenin leads to a delayed and fibrous fracture repair process, and Nefopam inhibits β-catenin mediated signaling during skin wound repair3].

References:
[1]. Kim KH, et al. Rediscovery of nefopam for the treatment of neuropathic pain. Korean J Pain. 2014 Apr;27(2):103-11.