CAS NO: | 1384424-80-9 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 1384424-80-9 |
化学名 | (Z)-N'-(7-methoxyquinolin-4-yl)-N-(6-(trifluoromethyl)pyridin-2-yl)carbamimidic acid |
Canonical SMILES | COC1=CC2=NC=CC(/N=C(O)/NC3=CC=CC(C(F)(F)F)=N3)=C2C=C1 |
分子式 | C17H13F3N4O2 |
分子量 | 362.31 |
溶解度 | <36.23mg/ml in DMSO |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain[1]. References: |