| CAS NO: | 1155773-15-1 |
| 包装: | 5mg |
| 市场价: | 3234元 |
| Cas No. | 1155773-15-1 |
| Canonical SMILES | CCN1C(N2CC3=CC(OC)=CC(OC)=C3[C@H](C=C2C14CCN(CC4)CC5=CC(C)=CC(C)=C5)C)=O |
| 分子式 | C30H39N3O3 |
| 分子量 | 489.65 |
| 溶解度 | ethanol|2.45|5withgentlewarming|DMSO|0.98|2withgentlewarming| |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Potent EP4 receptor antagonist (IC50 = 59 nM). Suppresses EP4-mediated Th1 differentiation, Th17 cell expansion, and IL-23 secretion by activated dendritic cells. Inhibits Th1 and Th17 cytokine production, suppresses collagen- and GPI-induced arthritis in mice. Attenuates CFA-induced inflammatory pain in rats. Analgesic. Orally bioavailable. |
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