| CAS NO: | 1279029-79-6 |
| 包装 | 价格(元) |
| 500µg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 1279029-79-6 |
| 别名 | [2H5]-喹那普利 |
| Canonical SMILES | O=C(O)[C@H]1N(C([C@H](C)N[C@@H](CCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C(OCC)=O)=O)CC3=C(C=CC=C3)C1 |
| 分子式 | C25H25D5N2O5 |
| 分子量 | 443.6 |
| 溶解度 | Methanol: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Quinapril-d5is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat.1,2In vivo, quinapril (3 mg/kg) reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats.2It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril (10-200 mg/kg) prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations containing quinapril have been used in the treatment of hypertension, heart failure, and diabetic nephropathy. 1.Vago, T., Bevilacqua, M., Conci, F., et al.Angiotensin converting enzyme binding sites in human heart and lung: Comparison with rat tissuesBr. J. Pharmacol.107(3)821-825(1992) 2.Kaplan, H.R., Taylor, D.G., and Olson, S.C.Quinapril: Overview of preclinical dataClin. Cardiol.13(6 Suppl. 7)VII6-VII12(1990) |
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