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1,2,3,4,5,6-Hexabromocyclohexane
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1,2,3,4,5,6-Hexabromocyclohexane图片
CAS NO:1837-91-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
1,2,3,4,5,6-六溴环己烷是一种溴代烃,是一种有效的 JAK2 酪氨酸激酶自磷酸化抑制剂。
Cas No.1837-91-8
别名1,2,3,4,5,6-六溴化环己烷
化学名1,2,3,4,5,6-hexabromocyclohexane
Canonical SMILESC1(C(C(C(C(C1Br)Br)Br)Br)Br)Br
分子式C6H6Br6
分子量557.54
溶解度≥ 8.2mg/mL in DMSO with gentle warming
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述 Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.