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Indomethacin-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Indomethacin-d4图片
CAS NO:87377-08-0
包装与价格:
包装价格(元)
500μg电议
1mg电议

产品介绍
Indomethacin-D4 (Indometacin-D4) 是一种氘标记的吲哚美辛。
Cas No.87377-08-0
别名吲哚美辛-D4; Indometacin-d4
Canonical SMILESCC1=C(CC(O)=O)C(C=C(OC)C=C2)=C2N1C(C3=C([2H])C([2H])=C(Cl)C([2H])=C3[2H])=O
分子式C19H12ClD4NO4
分子量361.8
溶解度DMF: 20 mg/ml,DMSO: 18 mg/ml,Ethanol: 7 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Indomethacin-d4 is intended for use as an internal standard for the quantification of indomethacin by GC- or LC-MS. Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in rabbits. It also reduces paw edema in a rat model of carrageenan-induced inflammation.