您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > WYC-209
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
WYC-209
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
WYC-209图片
CAS NO:2131803-90-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
WYC-209是一种合成类视黄醇,能抑制恶性小鼠黑色素瘤肿瘤再生细胞(TRC)的增殖,IC50值为0.19μM。WYC-209主要细胞靶点是维甲酸受体(RARs)。
Cas No.2131803-90-0
别名4,5-二(羟甲基)-2-苯基-1H-咪唑
Canonical SMILESO=C(C1=CN=C(C#CC2=CC=C3C(C(C)(C)CCS3=O)=C2)N=C1)OCC
分子式C20H20N2O3S
分子量368.45
溶解度DMSO : 83.33 mg/mL (226.16 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

WYC-209 is a synthetic retinoid, which inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 of 0.19 μM. The primary cellular target of WYC-209 is retinoic acid receptors (RARs)[1]. Retinoic acid receptors[1]

[1]. Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406.