Asperphenamate 是扁平曲霉的一种真菌代谢物,具有抗癌作用,在 T47D、MDA-MB-231 和 HL-60 细胞中的 IC50 值分别为 92.3 μM、96.5 μM 和 97.9 μM。
Cas No. | 63631-36-7 |
Canonical SMILES | O=C(N[C@@H](CC1=CC=CC=C1)COC([C@H](CC2=CC=CC=C2)NC(C3=CC=CC=C3)=O)=O)C4=CC=CC=C4 |
分子式 | C32H30N2O4 |
分子量 | 506.6 |
溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Asperphenamate is a fungal secondary metabolite originally isolated from A. flavipes. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM). |