Pinosylvin 是一种从 Pinus spp 的心材中分离出来的感染前的二苯乙烯类毒素，具有抗菌活性 。
| Cas No. | 22139-77-1 |
| 别名 | 赤松素 |
| Canonical SMILES | OC1=CC(/C=C/C2=CC=CC=C2)=CC(O)=C1 |
| 分子式 | C14H12O2 |
| 分子量 | 212.2 |
| 溶解度 | DMF: 10mg/mL,DMF:PBS (pH 7.2) (1:50): 0.01mg/mL,DMSO: 10mg/mL,Ethanol: 20mg/mL,Ethanol:PBS (pH 7.2) (1:50): 0.01mg/mL |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pinosylvin is a stilbene originally isolated from pine heartwood that has diverse biological activities. It activates sirtuin 1 (SIRT1) and induces glucose uptake in isolated rat L6 skeletal muscle myotubes. Pinosylvin reduces radial growth in a panel of 28 plant pathogenic fungi when used at a concentration of 100 μg/ml. It reduces expression of matrix metalloproteinase-2 (MMP-2), MMP-9, and membrane type 1-MMP in and inhibits migration of HT-1080 cells. Pinosylvin (10 mg/kg, i.p.) reduces the number of tumor nodules and lung tumor weight in a CT26 mouse xenograft model of metastatic colon cancer. It decreases hind paw volume and myeloperoxidase (MPO) activity in a rat model of adjuvant-induced arthritis. Pinosylvin also exhibits plant antifeedant activity against L. americanus (snowshoe hares). |
m.cnreagent.com