4-羟基甲苯磺丁脲 (Hydroxytolbutamide) 是甲苯磺丁脲的代谢物。
Cas No. | 5719-85-7 |
别名 | 4-羟基甲苯磺丁脲,Hydroxytolbutamide |
Canonical SMILES | CCCCNC(=O)NS(=O)(=O)c1ccc(CO)cc1 |
分子式 | C12H18N2O4S |
分子量 | 286.4 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker. Tolbutamide 4-hydroxylation is an often used probe reaction in the pharmaceutical industry for the characterization of CYP2C8 and CYP2C9 involvement in the metabolism of clinical drugs. |