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1-Monomyristin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Monomyristin图片
CAS NO:589-68-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
1-Monomyristin 提取自 Serenoa repens,抑制 2-油酰甘油的水解 (IC50=32 μM) 和脂肪酸酰胺水解酶 (FAAH) 活性 (IC50=18 μM)。1-Monomyristin 对金黄色葡萄球菌和聚集性放线菌有抗菌活性,对白色念珠菌也有抗真菌活性。
Cas No.589-68-4
别名1-肉豆蔻酸单甘油酯
Canonical SMILESCCCCCCCCCCCCCC(OCC(O)CO)=O
分子式C17H34O4
分子量302.45
溶解度DMSO: 250 mg/mL (826.58 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3]. Human Endogenous Metabolite

[1]. Shimada H, et al. Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens). J Nat Prod. 1997 Apr;60(4):417-8. [2]. Vandevoorde S, et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochem Biophys Res Commun. 2005 Nov 11;337(1):104-9. [3]. Jumina, et al. Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents. Molecules. 2018 Nov 29;23(12). pii: E3141