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H-Gly-Arg-pNA(hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
H-Gly-Arg-pNA(hydrochloride)图片
CAS NO:125455-61-0
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
 
Cas No.125455-61-0
Canonical SMILESO=C([C@@H](NC(CN)=O)CCCNC(N)=N)NC1=CC=C([N+]([O-])=O)C=C1.Cl.Cl
分子式C14H21N7O4.2HCl
分子量424.3
溶解度DMF: 20mg/mL,DMSO: 3mg/mL,PBS (pH 7.2): 3mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

H-Gly-Arg-pNA is a colorimetric substrate for thrombin.1,2 Thrombin preferentially binds to and cleaves the Gly-Arg (GR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.

References
1. Hortin, G.L., Warshawsky, I., and Laude-Sharp, M. Macromolecular chromogenic substrates for measuring proteinase activity. Clin. Chem. 47(2), 215-222 (2001).
2. Rijkers, D.T., Wielders, S.J., Tesser, G.I., et al. Design and synthesis of thrombin substrates with modified kinetic parameters. Thromb. Res. 79(5-6), 491-499 (1995).