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Pyrenophorol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Pyrenophorol图片
CAS NO:22248-41-5
包装:1mg
市场价:3311元

产品介绍
Pyrenophorol 是一种 C9H12O3 化合物，从植物病原真菌 Stemphylium radicinum, C.
Cas No.22248-41-5
Canonical SMILESO=C(O[C@H](C)CC[C@H](O)/C=C/1)/C=C/[C@@H](O)CC[C@@H](C)OC1=O
分子式C16H24O6
分子量312.4
溶解度DMSO: 5 mg/ml,Methanol: 5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pyrenophorol is a fungal metabolite that has been found in Alternaria and has diverse biological activities.1,2,3 It inhibits human topoisomerase II α when used at concentrations of 75 and 100 μM.1 It is active against S. cerevisiae (MIC = 4 μM) and M. violaceum.2 Pyrenophorol induces leaf necrosis and chlorophyll retention in wild oats when used at a concentration of 64 μM.3

References
1. Jarolim, K., Del Favero, G., Ellmer, D., et al. Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase. Arch. Toxicol. 91(4), 2007-2016 (2016).
2. Sumarah, M.W., Kesting, J.R., S•rensen, D., et al. Antifungal metabolites from fungal endophytes of Pinus strobus. Phytochemistry 72(14-15), 1833-1837 (2011).