Dolastatin 15 (DLS 15) 是一种源自 Dolabella auricularia 的缩肽,是一种有效的抗有丝分裂剂,在结构上与抗微管蛋白剂 Dolastatin 10 相关。Dolastatin 15 在多发性骨髓瘤细胞中诱导细胞周期停滞和细胞凋亡。 Dolastatin 15 可用作 ADC 细胞毒素。
Cas No. | 123884-00-4 |
别名 | DLS 15 |
分子式 | C45H68N6O9 |
分子量 | 837.07 |
溶解度 | Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic |