Tubulin inhibitor 6

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Tubulin inhibitor 6

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

105925-39-1

包装与价格：

包装	价格(元)
10mM (in 1mL DMSO)	电议
5mg	电议
10mg	电议

产品介绍

Tubulin inhibitor 6 (Compound 14b) 是一种微管蛋白 (tubulin) 抑制剂，也是多种肿瘤细胞系的有效抑制剂。Tubulin inhibitor 6 抑制微管蛋白聚合，IC50 为 0.87 μM。Tubulin inhibitor 6 抑制 K562 细胞生长，IC50 为 840 nM。

Cas No.	105925-39-1
Canonical SMILES	O=C(N1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13)C4=CC=C(OC)C=C4
分子式	C₂₀H₁₄ClNO₂S
分子量	367.85
溶解度	DMSO: 62.5 mg/mL (169.91 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1]. [1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.