| CAS NO: | 6812-98-2 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 6812-98-2 |
| 别名 | 地榆皂苷元 |
| 分子式 | C30H46O3 |
| 分子量 | 454.68 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA)[1]. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. The expression of blaR1, mecA and blaZ is significantly inhibited in MRSA in a dose-dependent manner when it is treated with sub-MIC (1.56-6.25 μg/mL) concentrations of Sanguisorbigenin. Sanguisorbigenin remarkably reduces the gene expression of mecA. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decrease PBP2a expression[1]. [1]. S Wang, et al. Antibacterial activity and synergy of antibiotics with sanguisorbigenin isolated from Sanguisorba officinalis L. against methicillin-resistant Staphylococcus aureus. Lett Appl Microbiol. 2021 Mar;72(3):238-244. |
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