CAS NO: | 2229974-73-4 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 2229974-73-4 |
分子式 | C53H67N11O7S |
分子量 | 1002.23 |
溶解度 | DMSO : 50 mg/mL (49.89 mM; Need ultrasonic) |
储存条件 | Store at -20°C, sealed storage, away from moisture and light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity[1]. XY028-133 (1 and 3 μM, 24 h) significantly decreases CDK4/6, Cyclin A, PLK1 and pRb protein levels in A375 cells[1]. [1]. JIN, Jian, et al. COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER. Patent. US2017/065027. |