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IRAK4-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IRAK4-IN-4图片
CAS NO:1850276-58-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
IRAK4-IN-4 是一种白介素-1 受体相关激酶 (IRAK4) 抑制剂,IC50 为 2.8 nM。详细信息请参考专利文献 CN107163044A 中的化合物 15。IRAK4-IN-4 还抑制环 GMP-AM 合酶 (cGAS),IC50 为 2.1 nM。
Cas No.1850276-58-2
Canonical SMILESO=C(C1=C(C2=CC=CC=C2)N=C3C=C(C)C=CN31)C(C4=CC=CC=C4)=O
分子式C22H16N2O2
分子量340.37
溶解度DMSO: 25 mg/mL (73.45 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM[1].

[1]. One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.