CAS NO: | 1268356-17-7 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 1268356-17-7 |
别名 | 尼罗替尼-D6,AMN107-d6 |
Canonical SMILES | O=C(NC1=CC(C(F)(F)F)=CC(N2C=C(C)N=C2)=C1)C3=C([2H])C(NC4=NC=CC(C5=CC=CN=C5)=N4)=C(C([2H])([2H])[2H])C([2H])=C3[2H] |
分子式 | C28H16D6F3N7O |
分子量 | 535.55 |
溶解度 | DMF: 3 mg/ml,DMSO: 10 mg/ml |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Nilotinib D6 (AMN107 D6) is a deuterium labeled Nilotinib. Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity[1]. [1]. Weisberg E, et al. Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias. Blood. 2007 Mar 1;109(5):2112-20. |