CAS NO: | 137868-52-1 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 137868-52-1 |
别名 | UDP-Α-D半乳糖二钠盐 |
Canonical SMILES | O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@H]([C@H]1O)COP(OP(O[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)([O-])=O)([O-])=O.[Na+].[Na+] |
分子式 | C15H23N2Na2O17P2 |
分子量 | 611.27 |
溶解度 | PBS (pH 7.2): 10 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | UDP-α-D-galactose is an endogenous nucleotide sugar that is used by glycosyltransferases to transfer α-D-galactose residues to substrates.1It is an agonist of the purinergic P2Y14receptor (EC50= 0.67 µM), an atypical P2Y receptor involved in the activation of dendritic and glial cells.2Levels of UDP-α-D-galactose in red blood cells are decreased in patients with phenylketonuria (PKU) and maple syrup urine disease, inborn errors of amino acid metabolism characterized by mutations in the gene encoding phenylalanine hydroxylase (PAH) and a deficiency in the branched-chain α-keto acid dehydrogenase enzyme complex, respectively.3 1.Hennet, T.The galactosyltransferase familyCell Mol. Life Sci.59(7)1081-1095(2002) 2.Jacobson, K.A., Ivanov, A.A., de Castro, S., et al.Development of selective agonists and antagonists of P2Y receptorsPurinergic Signal.5(1)75-89(2009) 3.Gibson, J.B., Berry, G.T., Palmieri, M.J., et al.Sugar nucleotide concentrations in red blood cells of patients on protein- and lactose-limited diets: Effect of galactose supplementationAm. J. Clin. Nutr.63(5)704-708(1996) |