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m-Methoxybenzamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
m-Methoxybenzamide图片
CAS NO:5813-86-5
包装与价格:
包装价格(元)
5 g电议
10 g电议
25 g电议

产品介绍
m-Methoxybenzamide (3-MBA) 是 ADP-核糖基转移酶 (ADPRTs) 和 PARP 的抑制剂,可抑制枯草芽孢杆菌中的细胞分裂,导致细胞丝状化并最终裂解。 m-Methoxybenzamide (3-MBA) 可增强蓝马铃薯 (Solanum tuberosum L. subsp. andigenum) 的体外植物生长、微块茎化和转化效率。
Cas No.5813-86-5
别名3-甲氧基苯甲酰胺,3-MBA
Canonical SMILESCOC1=CC=CC(C(N)=O)=C1
分子式C8H9NO2
分子量151.2
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml,Ethanol: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

m-Methoxybenzamide is an inhibitor of poly(ADP-ribose) polymerase (PARP; Ki=<2 µm).1It also inhibits human placental ADP ribosyl transferase activity by 93% when used at a concentration of 100 µM.2m-Methoxybenzamide (100, 200, and 300 mg/kg) increases the pain threshold in the paw pinch test in rats.3

1.Purnell, M.R., and Whish, W.J.Novel inhibitors of poly(ADP-ribose) synthetaseBiochem. J.185(3)775-777(1980) 2.Burtscher, H.J., Auer, B., Klocker, H., et al.Isolation of ADP-ribosyltransferase by affinity chromatographyAnal. Biochem.152(2)285-290(1986) 3.Sanders, R., Dill, R.E., Dorris, R.L., et al.Analgesic effects of 3-methoxybenzamide in ratsJ. Pharm. Pharmacol.41(4)268-269(1989)