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(E)-Methyl 4-coumarate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(E)-Methyl 4-coumarate图片
CAS NO:19367-38-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
(E)-Methyl4-coumarate(Methyl4-hydroxycinnamate)在几种植物中发现,如葱(Alliumcepa)或noni(MorindacitrifoliaL.)叶中。(E)-Methyl4-coumarate与CarnosicAcid联用可诱导细胞凋亡,杀死急性髓性白血病细胞,但不能杀死正常的外周血单核细胞。(E)-Methyl4-coumarate具有抗氧化和抗菌活性。
Cas No.19367-38-5
别名4-羟基肉桂酸甲酯; Methyl trans-p-coumarate
Canonical SMILESO=C(OC)/C=C/C1=CC=C(O)C=C1.[E]
分子式C10H10O3
分子量178.18
溶解度DMSO: 100 mg/mL (561.23 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as green onion (Allium cepa) or noni (Morinda citrifolia L.) leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity.

[1]. Trachtenberg A, et al. Synergistic Cytotoxicity of Methyl 4-Hydroxycinnamate and Carnosic Acid to Acute Myeloid Leukemia Cells via Calcium-Dependent Apoptosis Induction. Front Pharmacol. 2019 May 9;10:507.