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MS7972
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MS7972图片
CAS NO:352553-42-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
MS7972 是一种阻断人 p53 和 CREB 结合的小分子。MS7972 在50 μM 的时候几乎可以完全阻断 BRD 的相互作用。
Cas No.352553-42-5
分子式C14H13NO2
分子量227.26
溶解度DMSO : 100 mg/mL (440.02 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1].

Addition of MS7972 to the CBP BRD results in emission at 445 nm and quenching of the CBP BRD due to resonance energy transfer[1].

[1]. Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13(1):81-90.