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FPL 55712(sodium salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
FPL 55712(sodium salt)图片
CAS NO:40786-08-1
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A leukotriene receptor antagonist
Cas No.40786-08-1
Canonical SMILESO=C(C(OC1=C(CCC)C(OCC(COC2=C(CCC)C(O)=C(C(C)=O)C=C2)O)=CC=C13)=CC3=O)[O-].[Na+]
分子式C27H29O9• Na
分子量520.5
溶解度DMSO: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FPL 55712 (sodium salt) is a leukotriene (LT) receptor antagonist.1It inhibits the binding of LTD4to guinea pig lung homogenates (IC50= 4 µM) and reduces LTD4-induced contraction of isolated guinea pig tracheal smooth muscle (pA2= 1 µM). FPL 55712 (sodium salt) inhibits bronchoconstriction induced by LTD4, LTC4, or LTE4in guinea pigs (ID50s = 2, 6, and 1 mg/kg, respectively).

1.Cohen, N., Weber, G., Banner, B.L., et al.3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonistsJ. Med. Chem.32(8)1842-1860(1989)