BSB 是一种刚果红衍生的荧光探针。BSB 不仅与细胞外淀粉样 β 蛋白结合,还与许多由异常 tau 和突触核蛋白组成的细胞内病变结合。BSB 作为阿尔茨海默病的原型成像剂。
Cas No. | 291766-06-8 |
别名 | (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene |
分子式 | C24H17BrO6 |
分子量 | 481.29 |
溶解度 | DMSO : 100 mg/mL (207.77 mM; ultrasonic and warming and heat to 60°C) |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease[1]. |