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Beraprost(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Beraprost(sodium salt)图片
CAS NO:88475-69-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.88475-69-8
别名贝前列素钠
Canonical SMILESO[C@H]1C(/C=C/[C@@H](O)C(C)CC#CC)[C@@H](C(C=CC=C2CCCC([O-])=O)=C2O3)[C@@H]3C1.[Na+]
分子式C24H29O5•Na
分子量420.5
溶解度DMF: 77 mg/ml,DMSO: 43 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 19 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. This modification increases the plasma half-life from 30 seconds to several hours, and permits the compound to be taken orally. Doses of 20-100 µg in humans, given 1 to 3 times per day, have been demonstrated to improve clinical end points in diseases responsive to prostacyclin. Oral beraprost therapy improved the survival and pulmonary hemodynamics of patients with primary pulmonary hypertension. Beraprost inhibits platelet aggregation in healthy subjects and in diabetic patients at similar doses.