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Avasopasem manganese
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Avasopasem manganese图片
CAS NO:435327-40-5
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
Avasopasem manganese (GC4419;M-40419) 是一种有效的超氧化物歧化酶，能迅速和特异性地将 O2*- 转化为过氧化氢 (H2O2)，阻止这一级联反应的启动。Avasopasem manganese 可用于严重口腔黏膜炎 (SOM) 和癌症的研究。
Cas No.435327-40-5
别名GC-4419; M-40419
分子式C21H31Cl2MnN5
分子量479.35
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer[1].

Avasopasem manganese is an agent intended to interrupt severe oral mucositis pathogenesis, to reduce the duration, incidence, and severity of radiation-induced oral mucositis[1].

[1]. Anderson CM, et al. Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer [published correction appears in J Clin Oncol. 2020 Jan 20;38(3):288]. J Clin Oncol. 2019;37(34):3256-3265.