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Abacavir hydroxyacetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Abacavir hydroxyacetate图片
CAS NO:1446418-48-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Abacavir hydroxyacetate 是一个具有口服活性的 IL-20 和 PRINS 的抑制剂。Abacavir hydroxyacetate 作为免疫调节剂,降低牛皮癣的增殖率。Abacavir hydroxyacetate 可用于炎症型皮肤病的研究。
Cas No.1446418-48-9
分子式C16H20N6O3
分子量344.37
溶解度DMSO : ≥ 100 mg/mL (290.39 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Abacavir hydroxyacetate is an orally active inhibitor ofIL-20andPRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems[1][2].

Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice[2].

Animal Model:6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue[2]
Dosage:10 and 20 mg/kg
Administration:Oral gavage; 10-20 mg/kg once
Result:Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.