2-HOBA (2-HOBA) 是一种选择性的二羰基清除剂，是一种抗氧化剂和自由基和异左旋糖苷 (IsoLGs) 的清除剂。
| Cas No. | 932-30-9 |
| 别名 | 2-羟基苄胺,2-HOBA |
| Canonical SMILES | OC1=C(CN)C=CC=C1 |
| 分子式 | C7H9NO |
| 分子量 | 123.2 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2-HOBA is an isoketal scavenger. In vivo, 2-HOBA reduces angiotensin II-induced increases in blood pressure and decreases isoketal accumulation in mouse heart and vasculature. It also prevents angiotensin II-induced collagen IV accumulation and renal damage in mouse kidney. 2-HOBA has also been used as a building block in the synthesis of saluretic agents and task-specific ionic liquids. |
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