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2-Deoxy-D-glucose 6-phosphate disodium
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-Deoxy-D-glucose 6-phosphate disodium图片
CAS NO:33068-19-8
包装与价格：
包装价格(元)
10mg电议
25mg电议
50mg电议

产品介绍
2-Deoxy-D-glucose 6-phosphate disodium 是 2-Deoxy-D-glucose 的衍生物，在哺乳动物细胞中由己糖激酶作用于 2-DG 产生。2-Deoxy-D-glucose 6-phosphate disodium 是葡萄糖代谢的竞争性抑制剂，通过对己糖激酶的作用抑制糖酵解。
Cas No.33068-19-8
别名2-脱氧-D-葡萄糖-6-磷酸钠盐
分子式C6H11Na2O8P
分子量288.1
溶解度Water : 250 mg/mL (867.75 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].

[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.